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Mary L. Affronti


Clinical Professor, Nurse Practitioner, Primary Investigator

Duke University

North Carolina

Mary Lou Affronti is currently a Clinical Professor at the Duke School of Nursing in Durham, North Carolina and the Duke Cancer Institute’s Preston Robert Brain Tumor Center.

Dr. Affronti's clinical research practice spanning over 35 years in the area of bone marrow transplant and brain tumors focuses on the development of clinical trials and practice improvement projects to ameliorate cancer symptoms, increase quality of life and improve survival for individuals with the most life-limiting cancer diagnoses. As a primary investigator, she develops and leads therapeutic/supportive care research while seeing patients as a nurse practitioner and educating graduate students. Dr. Affront’s research has received >$2.4 million in extra-mural funding creating an impact evident by >100 international presentations and >40 peer-reviewed publications. Examples are her innovative approach for increasing adherence to ordering evidence-based guideline antiemetics by embedding them into computerized, chemotherapy order-sets and consulting work on an Oncology Nursing Society antiemetic survey published in the multinational journal, Supportive Care in Cancer. Dr. Affronti is Lead Faculty for the #1 2020 US Adult Gerontology Nurse Practitioner Program. She was invited by the NIH as a leading neuro-oncology nurse research scholar and symptom management expert to evaluate the NCI’s Neuro-Oncology Branch. Dr. Affronti’s scholarship has received international accolades for her research to improve the lives of individuals with cancer.
Dr. Mary Lou Affronti completed her BSN from The University of Delaware, MSN and DNP degrees at the Duke School of Nursing and a Masters in Clinical Research from the Duke School of Medicine.

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